Method for determining 46 antibiotics in water based on solid phase extraction-ultra-high performance liquid chromatography-electrostatic field orbitrap mass spectrometry

The invention belongs to the field of water quality detection, and particularly relates to a method for determining 46 antibiotics in water based on solid phase extraction (SPE)-ultra-high performance liquid chromatography (UPLC)-electrostatic field orbitrap mass spectrometry (Q-orbitrap). The method comprises the following steps: firstly, preparing a standard solution; then carrying out sample treatment; and finally, detecting by adopting ultra-high performance liquid chromatography-electrostatic field orbitrap mass spectrometry. Compared with the prior art, the method for detecting the 46 antibiotics in the environmental water by using the ultra-high performance liquid chromatography (UPLC)-electrostatic field orbitrap mass spectrometry (Q-orbitrap) is established, compared with the prior art, the method can cover more types and numbers of target objects, and the pretreatment method provided by the invention can effectively improve the extraction efficiency of the target objects, so that the method can be u