Bionic bone scaffold based on PL (G) A/HAp and preparation method and application thereof

The invention belongs to the technical field of biological materials, and relates to a bionic bone scaffold based on PL (G) A/HAp as well as a preparation method and application of the bionic bone scaffold. The preparation method comprises the following steps: on the basis of a polylactic acid-glycolic acid copolymer/hydroxyapatite (PLGA/HAp) inverse opal structure, respectively preparing hydroxyapatite (HAp) nano paper layers with certain thickness at the top end and the bottom end of the PLGA/HAp inverse opal structure through a suction filtration method; the outer surfaces of the HAp nanometer paper layers on the two sides are coated with polylactic acid (PLA) isolation layers with a certain thickness through a diffusion-evaporation self-film-forming method, finally, the bionic bone scaffold based on PL (G) A/HAp is constructed, the bionic bone scaffold is of a multi-layer and multi-stage micro-nano sandwich-like structure, and the highly bionic composite scaffold material more suitable for cranio-maxillof