Preparation method of intermediate for synthesizing SGLT inhibitor

The invention relates to a preparation method of an intermediate for synthesizing a sodium-dependent glucose co-transporter (SGLT) inhibitor. According to the invention, a compound of chemical formula 9, which is an important intermediate of a compound of chemical formula I of an SGLT inhibitor, can...

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Hauptverfasser: YOON YOUN JUNG, YOON HEE-KYOON
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a preparation method of an intermediate for synthesizing a sodium-dependent glucose co-transporter (SGLT) inhibitor. According to the invention, a compound of chemical formula 9, which is an important intermediate of a compound of chemical formula I of an SGLT inhibitor, can be obtained with high yield and high quality. According to the preparation method of the SGLT inhibitor, the SGLT inhibitor can be produced without a special device (such as an ozone generator), so that the economic feasibility can be greatly improved. 本发明涉及一种用于合成钠依赖性葡萄糖协同转运体(SGLT)抑制剂的中间体的制备方法。根据本发明,可获得高产率和高质量的化学式9化合物,其为SGLT抑制剂的化学式I化合物的重要中间体。由于本发明的SGLT抑制剂的制备方法不需特殊装置(诸如臭氧产生器)也可生产上述SGLT抑制剂,还可大幅改善经济可行性。