CD7 expression blockers and chimeric antigen receptors for T cell malignancy immunotherapy

The present invention provides compositions comprising an anti-CD7 chimeric activated receptor (CAR) and an anti-CD7 protein expression blocker, and methods of using such compositions in the treatment of cancer. 本发明提供了包含抗CD7嵌合活化受体(CAR)和抗CD7蛋白表达阻滞剂的组合物，及在癌症治疗中使用此类组合物的方法。...

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Bibliographische Detailangaben
Hauptverfasser:	KAMIYA TAKAHIRO, FANG YUTIAN, VENECA, NATASHA, CAMPANA DARIO
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention provides compositions comprising an anti-CD7 chimeric activated receptor (CAR) and an anti-CD7 protein expression blocker, and methods of using such compositions in the treatment of cancer. 本发明提供了包含抗CD7嵌合活化受体(CAR)和抗CD7蛋白表达阻滞剂的组合物，及在癌症治疗中使用此类组合物的方法。