Synthesis method of chlorantraniliprole intermediate

The invention relates to the technical field of chemical synthesis, and particularly discloses a synthetic method of a chlorantraniliprole intermediate. The synthesis method comprises the following steps that under the condition of an organic solvent, a compound I, brominated salt and concentrated s...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: HAN YONGXIAO, HUANG TAO, XIE MEIXIAN, ZHEN HUALIN, YANG HAIBO, FAN LIKE, SHEN YINSHAN, LUO JINLEI, GAO YONGCHAO, ZHANG YAJING
Format: Patent
Sprache:chi ; eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to the technical field of chemical synthesis, and particularly discloses a synthetic method of a chlorantraniliprole intermediate. The synthesis method comprises the following steps that under the condition of an organic solvent, a compound I, brominated salt and concentrated sulfuric acid serve as raw materials, a bromination reaction is conducted, a compound II is prepared, and the organic solvent is dichloroethane or chloroform; the molar ratio of the compound I to the sodium bromide is 1: (1-1.1); the molar ratio of the compound 1 to the concentrated sulfuric acid is 1: (2-4). According to the method, the bromination reaction is fully carried out due to the excessive use of concentrated sulfuric acid, so that the yield and the purity of the compound II are obviously improved, the yield can reach 95% or above, the purity can reach 98.0% or above, in addition, generation of a large amount of mixed acid wastewater is avoided, the types of three wastes are simplified, the environment-fri