Application of soybean extract in prevention or treatment of uranium-induced lung injury

The invention belongs to the technical field of lung injury treatment, and relates to application of a soybean extract in prevention or treatment of uranium-induced lung injury. Specifically, the invention provides an application of the soybean extract in preparation of a medicine, and the medicine...

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Bibliographische Detailangaben
Hauptverfasser: ZHAN JINGMING, YANG XUKUI, TANG YUFU, YANG XIN, LIANG HONGYING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of lung injury treatment, and relates to application of a soybean extract in prevention or treatment of uranium-induced lung injury. Specifically, the invention provides an application of the soybean extract in preparation of a medicine, and the medicine has one or more of the following applications: a) improving pulmonary fibrosis of a person exposed with uranium; b) improving the uranium discharge capability of the uranium exposer; and b) preventing or treating uranium-induced lung injury. The application studies and analyzes the protective effect of the soybean extract (SE) on a uranium-induced lung injury mouse model, the research result shows that the soybean extract can improve the pulmonary fibrosis of uranium-exposed people, SE treatment can relieve the uranium-induced pulmonary fibrosis, expression of alpha-SMA, TGF-beta1 and Hyp is reduced, lung histopathologic change caused by uranium is improved, and compared with a U group, the application has the adva