Comprehensive analysis method for searching peripheral nerve infringement markers of patients with head and neck malignant tumors
The invention discloses a comprehensive analysis method for finding a marker for finding whether a patient with head and neck malignant tumors has peripheral nerve invasion or not, and belongs to the technical field of biology. The method comprises the following steps: collecting original RNA sequen...
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| creator | ZHENG BOWEN ZHANG QIAN YANG DEMENG |
| description | The invention discloses a comprehensive analysis method for finding a marker for finding whether a patient with head and neck malignant tumors has peripheral nerve invasion or not, and belongs to the technical field of biology. The method comprises the following steps: collecting original RNA sequencing data and clinical features from a certain TCGA cancer species queue, and then dividing the original RNA sequencing data and clinical features into a PNI group and a non-PNI group; analyzing differentially expressed genes in the PNI group and the non-PNI group by using the R packet DESeq2, so as to correct the post Plt; the absolute value gt of the difference multiple is 0.05; 2 is used as a threshold value for screening differential genes; carrying out GO and KEGG pathway enrichment analysis on the differential genes; analyzing the differential genes by using minimum absolute contraction and selection operator (LASSO) regression analysis; the most key PNI related genes are obtained from LASSO analysis; calcula |
| format | Patent |
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The method comprises the following steps: collecting original RNA sequencing data and clinical features from a certain TCGA cancer species queue, and then dividing the original RNA sequencing data and clinical features into a PNI group and a non-PNI group; analyzing differentially expressed genes in the PNI group and the non-PNI group by using the R packet DESeq2, so as to correct the post Plt; the absolute value gt of the difference multiple is 0.05; 2 is used as a threshold value for screening differential genes; carrying out GO and KEGG pathway enrichment analysis on the differential genes; analyzing the differential genes by using minimum absolute contraction and selection operator (LASSO) regression analysis; the most key PNI related genes are obtained from LASSO analysis; calcula</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; ENZYMOLOGY ; HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATIONTECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING ORPROCESSING OF MEDICAL OR HEALTHCARE DATA ; INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MUTATION OR GENETIC ENGINEERING ; PHYSICS ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240823&DB=EPODOC&CC=CN&NR=118538297A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240823&DB=EPODOC&CC=CN&NR=118538297A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ZHENG BOWEN</creatorcontrib><creatorcontrib>ZHANG QIAN</creatorcontrib><creatorcontrib>YANG DEMENG</creatorcontrib><title>Comprehensive analysis method for searching peripheral nerve infringement markers of patients with head and neck malignant tumors</title><description>The invention discloses a comprehensive analysis method for finding a marker for finding whether a patient with head and neck malignant tumors has peripheral nerve invasion or not, and belongs to the technical field of biology. 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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATIONTECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING ORPROCESSING OF MEDICAL OR HEALTHCARE DATA INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTEDFOR SPECIFIC APPLICATION FIELDS MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS VINEGAR WINE |
| title | Comprehensive analysis method for searching peripheral nerve infringement markers of patients with head and neck malignant tumors |
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