Preparation method of photoinitiator 369

The invention discloses a preparation method of a photoinitiator 369, and belongs to the field of photoinitiator preparation. The preparation method comprises the following steps: (1) carrying out Ullmann C-N coupling on chlorobenzene and morpholine under the action of a first catalyst to obtain N-phenylmorpholine; (2) N-phenylmorpholine and phenylalanine are subjected to a Friedel-Crafts reaction, and a compound I is prepared; (3) carrying out an aminomethylation reaction on the compound I, formic acid and formaldehyde to prepare a compound II; and (4) reacting the compound II with iodoethane to obtain a crude product of the photoinitiator 369. By implementing the method, the process route can be simplified, the use of fluorobenzene, bromine and the like is avoided, and the yield is increased. 本发明公开了一种光引发剂369的制备方法，属于光引发剂制备领域。制备方法包括以下步骤：(1)氯苯与吗啉在第一催化剂的作用下发生乌尔曼C-N偶联，得到N-苯基吗啉；(2)N-苯基吗啉与苯丙氨酸经傅克反应，制得化合物I；(3)化合物Ⅰ与甲酸、甲醛进行氨甲基化反应，制得化合物Ⅱ；(4)化合物Ⅱ与碘乙烷反应，得到光引发剂369粗品。实施本发明，可简化工艺路线，避免氟苯、溴素等的使用，且提升收率。