Primer group for identifying TCR/BCR diversity of cynomolgus monkeys at single cell level

The invention relates to a primer group for identifying TCR/BCR diversity of cynomolgus monkeys at a single cell level, and belongs to the technical field of single cell sequencing. The invention provides a primer group for single cell level specificity identification of TCR and/or BCR diversity of...

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Hauptverfasser: FANG XING, GUO YANG, CHEN YUEDONG, WANG CHUNMING, HUANG JIN, WANG LILI, FU HONGQIN, FAN ZHAOFEI, ZHANG XIANGQIAN, ZHANG DANCHEN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to a primer group for identifying TCR/BCR diversity of cynomolgus monkeys at a single cell level, and belongs to the technical field of single cell sequencing. The invention provides a primer group for single cell level specificity identification of TCR and/or BCR diversity of cynomolgus monkeys. The primer group comprises a primer group targeting TCR and/or a primer group targeting BCR; the primer group of the target TCR comprises a primer group of the target TCRB and/or a primer group of the target TCRA; the BCR-targeting primer group comprises an IGHA-targeting primer group, an IGHD-targeting primer group, an IGHE-targeting primer group, an IGHG-targeting primer group, an IGHM-targeting primer group, an IGL-targeting primer group and/or an IGK-targeting primer group. By using the primer group, a specific identification method of TCR and BCR of the cynomolgus monkey at the single cell level can be realized, and meanwhile, the primer group can be compatible with the existing single cell