Nucleic acid aptamer of targeted EB virus and application of nucleic acid aptamer

The invention relates to a targeted EB virus nucleic acid aptamer and application thereof, and relates to the technical field of bioengineering. The nucleic acid aptamer comprises a targeting sequence, and the nucleic acid aptamer is specifically combined with gHgL protein of the EB virus. The aptam...

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Bibliographische Detailangaben
Hauptverfasser:	CHEN KANGHONG, LIU JIAXIN, PANG ZEFEN, ZHU DANDONG, FANG ZHIXIN, QIU JIANXIANG, YAN XIUKUI
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to a targeted EB virus nucleic acid aptamer and application thereof, and relates to the technical field of bioengineering. The nucleic acid aptamer comprises a targeting sequence, and the nucleic acid aptamer is specifically combined with gHgL protein of the EB virus. The aptamer can target the EB virus by being specifically combined with the gHgL protein, has high binding force and affinity with the gHgL protein, and can be used for diagnosis and treatment of the EB virus, molecular imaging, drug delivery and the like. 本发明涉及一种靶向EB病毒的核酸适配体及其应用，涉及生物工程技术领域。该核酸适配体包括靶向序列，所述核酸适配体与EB病毒的gHgL蛋白特异性结合。该适配体能够通过与gHgL蛋白特异性结合靶向EB病毒，且与gHgL蛋白具有较强的结合力、亲和力，能够用于EB病毒的诊断及治疗、分子成像、药物递送等方面。