Thermosensitive hydrogel as well as preparation method and application thereof

The invention relates to the technical field of hydrogel, and discloses thermo-sensitive hydrogel as well as a preparation method and application thereof. The invention provides a thermo-sensitive hydrogel which is prepared by mixing a pluronic F127 aqueous solution and a polyethylene glycol PEG aqu...

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Bibliographische Detailangaben
Hauptverfasser: LI YINUO, ZHAO LIJING, SAN ZHIQIANG, HE KANG, WU HAO
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention relates to the technical field of hydrogel, and discloses thermo-sensitive hydrogel as well as a preparation method and application thereof. The invention provides a thermo-sensitive hydrogel which is prepared by mixing a pluronic F127 aqueous solution and a polyethylene glycol PEG aqueous solution, and a preparation method comprises the following steps: mixing the pluronic F127 aqueous solution and the polyethylene glycol PEG aqueous solution with a certain concentration under a stirring condition, and continuously stirring for more than 2 hours to uniformly mix the components in the solution; and putting the mixed solution in a low-temperature environment of 0-5 DEG C, and continuously stirring for more than 5 hours, in the process, pluronic F127 gradually forms a three-dimensional network structure, and polyethylene glycol PEG is gradually fused, so that the tough and elastic hydrogel is formed. Compared with the traditional dressing stent, the prepared novel hydrogel dressing stent has the a