Indole heterocyclic compound with cyclin-dependent kinase inhibitory activity and preparation method and medical application thereof

The invention relates to an indole heterocyclic compound with cyclin-dependent kinase inhibition activity and a preparation method and medical application thereof. Specifically, the invention relates to a compound as shown in a general formula (I), a preparation method thereof, a pharmaceutical composition containing the compound, and application of the compound as a cyclin dependent kinase (CDK) inhibitor in drugs for preventing or treating abnormal cell growth such as cancer. Wherein the definition of each group in the general formula (I) is the same as that in the specification. # imgabs0 # 本发明涉及具有细胞周期蛋白依赖性激酶抑制活性的吲哚类杂环化合物及其制备方法和医药用途。具体地，本发明涉及通式(I)所示的化合物、其制备方法、含有该化合物的药物组合物，以及其作为细胞周期蛋白依赖性激酶(CDK)抑制剂在预防或治疗异常细胞生长如癌症的药物中的用途。其中通式(I)中的各基团的定义与说明书中的定义相同。#imgabs0#