Application of PTD-FNK in regulating and controlling development of pig cavity follicles

The invention belongs to the technical field of animal breeding, and particularly relates to application of PTD-FNK in regulating and controlling development of pig cavity follicles. According to the application disclosed by the invention, the PTD-FNK is found to reduce apoptosis of granular cells in follicles by inhibiting expression of apoptosis genes CASP3, Foxo1, Bim and FasL, reduce the number of atresia of the lumenal follicles and promote development of the lumenal follicles of pigs; meanwhile, the PTD-FNK improves the follicular development quantity and quality by improving the activity of granular cells and the activity of antioxidant enzyme SOD, the medicine for promoting the follicular development of pigs is prepared from the PTD-FNK and is used for animal breeding, a new thought is provided for improving the breeding efficiency and the breeding quality of animals, and important significance is achieved. 本发明属于动物繁育技术领域，具体涉及PTD-FNK在调控猪有腔卵泡发育中的应用。本发明发现PTD-FNK通过抑制凋亡基因CASP3、Foxo1、Bim和FasL的表达来降低卵泡中颗粒细胞的凋