Application of Brucella OMP16 monoclonal antibody in preparation of product for inhibiting Brucella

The invention belongs to the technical field of biological medicine, and particularly relates to application of a Brucella OMP16 monoclonal antibody to preparation of a product for inhibiting Brucella, the amino acid sequence of a heavy chain variable region of the Brucella OMP16 monoclonal antibody is shown as SEQ ID NO.1, and the amino acid sequence of a light chain variable region of the Brucella OMP16 monoclonal antibody is shown as SEQ ID NO.2. Through in-vivo and in-vitro tests, the invention verifies the potential of the OMP16 monoclonal antibody as a therapeutic antibody in treatment of brucellosis. 本发明属于生物医药技术领域，具体涉及一种布鲁氏菌OMP16单克隆抗体在制备抑制布鲁氏菌的产品中的应用，布鲁氏菌OMP16单克隆抗体的重链可变区氨基酸序列如SEQ ID NO.1所示，轻链可变区氨基酸序列如SEQ ID NO.2所示。经体内和体外试验，本发明验证了OMP16单克隆抗体作为一种治疗性抗体在治疗布鲁氏菌病上的潜力。