Pharmaceutical composition containing triptolide ketone and application of pharmaceutical composition in preparation of antitumor drugs

The invention discloses a pharmaceutical composition containing triptonide and application of the pharmaceutical composition in preparation of antitumor drugs, the pharmaceutical composition is composed of triptonide and abelsilis.The novel pharmaceutical composition is composed of triptonide and ab...

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Hauptverfasser: LIN QINGQING, ZHU YU, HUANG DUPING, ZHAO CHENGGUANG, LIU YUXIN, ZHU FANYUN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a pharmaceutical composition containing triptonide and application of the pharmaceutical composition in preparation of antitumor drugs, the pharmaceutical composition is composed of triptonide and abelsilis.The novel pharmaceutical composition is composed of triptonide and abelsilis.The triptonide and abelsilism are combined according to a specific proportion, and through the synergistic effect of the triptonide and the abelsilism, the pharmaceutical composition can be used for preparing antitumor drugs. The inhibition effect on triple-negative breast cancer cells is obviously improved, and meanwhile, formation of triple-negative breast cancer cell colonies can be remarkably inhibited. 本发明公开了一种含雷公藤内酯酮的药物组合物及其在制备抗肿瘤药物中的应用,该药物组合物由雷公藤内酯酮和阿贝西利组成,本发明通过将雷公藤内酯酮和阿贝西利按照特定的比例组成新的药物组合物,通过两者的协同作用,明显提高了对三阴性乳腺癌细胞的抑制作用,同时,能够显著抑制三阴性乳腺癌细胞集落形成。