Preparation method of low-molecular-weight sulfated glycosaminoglycan and skin care application of low-molecular-weight sulfated glycosaminoglycan

The invention relates to the technical field of cosmetics, and provides a preparation method and skin care application of low-molecular-weight sulfated glycosaminoglycans, and the low-molecular-weight sulfated glycosaminoglycans are obtained by taking heparinoid byproducts as raw materials, degrading and extracting. The low-molecular-weight glycosaminoglycan sulfate is a biological source material, has good skin-friendly performance, can better enter deep skin tissues due to low molecular weight, can inhibit zebrafish embryo neutrophil aggregation, has a remarkable soothing effect, can promote zebrafish I-type collagen gene expression, and can be used for preparing the zebrafish I-type collagen protein. The composition has the effect of promoting regeneration of type I collagen, supports the claim of anti-wrinkle and tightening effects, and has a wide prospect of being developed into anti-aging cosmetics. According to the technical scheme, the problem that the heparinoid by-product cannot be utilized in the r