VAR2CSA recombinant protein as well as preparation method and application thereof

The invention belongs to the field of biological medicine, and relates to a VAR2CSA recombinant protein and a preparation method and application thereof. According to the VAR2CSA recombinant protein and the preparation method thereof provided by the invention, the VAR2CSA recombinant protein has goo...

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Bibliographische Detailangaben
Hauptverfasser:	ZHANG WENBIN, HE YONGQIAO, JIA WEIHUA, WU ZIYI, ZHANG PEIFEN, MU QUANKAI
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention belongs to the field of biological medicine, and relates to a VAR2CSA recombinant protein and a preparation method and application thereof. According to the VAR2CSA recombinant protein and the preparation method thereof provided by the invention, the VAR2CSA recombinant protein has good stability and relatively high yield, also has good detection efficiency of ofCS and glycoprotein thereof, can be used for large-scale production of detection protein of ofCS/ofCSPG, and is used for early screening, diagnosis, tumor load monitoring and prognosis prediction of malignant tumors. 本申请属于生物医药领域，涉及一种VAR2CSA重组蛋白及其制备方法和应用。本申请提供的VAR2CSA重组蛋白及其制备方法，具有良好的稳定性及较高的产量，同时兼具良好的ofCS及其糖蛋白的检测效能，可用于大规模生产ofCS/ofCSPG的检测蛋白，用于恶性肿瘤的早期筛查、诊断、肿瘤负荷监测及预后预测。