Geraniol derivative containing pyridine structure as well as preparation method and application of geraniol derivative

The invention discloses a geraniol derivative containing a pyridine structure as well as a preparation method and application of the geraniol derivative, and belongs to the field of medicinal chemistry. The geraniol derivative containing the pyridine structure has a structure as shown in the following formula: # imgabs0 #, wherein R is selected from a substituted or unsubstituted pyridine group. The derivatives show inhibitory activity on multifunctional oxidase (MFO) and carboxylesterase (EST) in adult aedes albopictus, and can be used for preparing anti-mosquito products. The invention also provides a preparation method and application of the geraniol derivative containing the pyridine structure. 本发明公开了一种含吡啶结构的香叶醇衍生物及其制备方法和应用，用于药物化学领域。本发明所述含吡啶结构的香叶醇衍生物具有如下式所示的结构：#imgabs0#式中，R选自取代或未取代的吡啶基团。该类衍生物都表现出了对白蚊伊蚊成蚊体内多功能氧化酶(MFO)、羧酸酯酶(EST)的抑制活性，可以用于制备抗蚊产品。本发明还提供含吡啶结构的香叶醇衍生物的制备方法和应用。