Image noise reduction method and device, equipment and medium

The invention discloses an image noise reduction method and device, equipment and a medium, and relates to the field of image processing, and the method comprises the steps: obtaining a distillation data pair constructed through a reference noise reduction model; the distillation data pair is constructed based on RAW domain noisy data and RGB domain noise reduction data processed by the reference noise reduction model and corresponding to the RAW domain noisy data; rGB domain reverse distillation is carried out on a first noise reduction model according to the distillation data constructed through the reference noise reduction model, a target noise reduction model is obtained, and the first noise reduction model is a noise reduction model obtained through synthetic noise data training; and performing image noise reduction through the target noise reduction model. According to the method, the RGB domain reverse distillation is performed on the first noise reduction model through the distillation data, so that