Tumor-targeted agonistic CD28 antigen binding molecules

The present invention relates to tumor-targeting bispecific agonistic antigen-binding molecules characterized by monovalent binding to CD28, methods for their preparation, pharmaceutical compositions containing these antibodies, and methods for their use. 本发明涉及以与CD28单价结合为特征的靶向肿瘤的双特异性激动性抗原结合分子、其制备方法、含有这些抗体的药物组合物以及使用它们的方法。