Nucleic acid-lipid nanoparticle compound for treating dyslipidemia disease and application thereof
The invention provides a nucleic acid-lipid nanoparticle compound for treating dyslipidemia diseases and an application of the nucleic acid-lipid nanoparticle compound, and the nucleic acid-lipid nanoparticle compound comprises nucleic acid for expressing choline phosphorylcytidyltransferase (CCT) p...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Format: | Patent |
| Sprache: | chi ; eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| Zusammenfassung: | The invention provides a nucleic acid-lipid nanoparticle compound for treating dyslipidemia diseases and an application of the nucleic acid-lipid nanoparticle compound, and the nucleic acid-lipid nanoparticle compound comprises nucleic acid for expressing choline phosphorylcytidyltransferase (CCT) protein and lipid nanoparticles, and the nucleic acid-lipid nanoparticle compound is a nucleic acid-lipid nanoparticle compound for treating dyslipidemia diseases and an application of the nucleic acid-lipid nanoparticle compound for treating dyslipidemia diseases and an application of the nucleic acid-lipid nanoparticle compound for treating the dyslipidemia diseases and the application of the nucleic acid-lipid nanoparticle compound for treating the dyslipidemia diseases. After the nucleic acid-lipid nanoparticle compound is used for treatment, the triglyceride level of the mouse liver can be reduced and maintained, which indicates that the novel nucleic acid-lipid nanoparticle compound has potential application v |
|---|