Salmon calcitonin-phospholipid complex chitosan nanoparticles, coating preparation thereof, preparation method and application of salmon calcitonin-phospholipid complex chitosan nanoparticles

The invention belongs to the field of medicines, and relates to salmon calcitonin phospholipid complex chitosan nanoparticles as well as a coating preparation, a preparation method and application of the salmon calcitonin phospholipid complex chitosan nanoparticles. The invention relates to coated s...

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Hauptverfasser: ZHANG JINGXIA, ZHANG HONGYAO, GUO YUHONG, ZHANG YING, ZHANG RUINI, LI JIANGHONG, DONG KAITAI, PENG JINCHUAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the field of medicines, and relates to salmon calcitonin phospholipid complex chitosan nanoparticles as well as a coating preparation, a preparation method and application of the salmon calcitonin phospholipid complex chitosan nanoparticles. The invention relates to coated salmon calcitonin phospholipid complex chitosan nanoparticles which can be orally taken, and the coated salmon calcitonin phospholipid complex chitosan nanoparticles are prepared by adding 7-50mg of a carrier material and 0-60mg of a surfactant into every 5mg of salmon calcitonin in a salmon calcitonin phospholipid complex. The shell salmon calcitonin phospholipid complex glycan nanoparticle is designed on the basis of a salmon calcitonin phospholipid complex, chitosan and phospholipid can form the chitosan-phospholipid nanoparticle through self-assembly, a chemical cross-linking agent does not need to be adopted, the preparation method is simple, no intermediate product is involved, and the chitosan-phospholipid na