Modified MRNA vaccine encoding herpes simplex virus glycoprotein and use thereof

The present invention provides compositions for the prevention and treatment of genital herpes comprising nucleoside modified mRNA encoding a herpes simplex virus (HSV) glycoprotein, including mRNA involved in viral entry and immune escape, and methods of use thereof. 本发明提供了用于预防和治疗生殖器疱疹的组合物,其包含编码单纯疱...

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Hauptverfasser: AWASTHI, SRIKANTH, FRIEDMANN, HARRY, WEISSMANN DINAH, COHEN GUY
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creator AWASTHI, SRIKANTH
FRIEDMANN, HARRY
WEISSMANN DINAH
COHEN GUY
description The present invention provides compositions for the prevention and treatment of genital herpes comprising nucleoside modified mRNA encoding a herpes simplex virus (HSV) glycoprotein, including mRNA involved in viral entry and immune escape, and methods of use thereof. 本发明提供了用于预防和治疗生殖器疱疹的组合物,其包含编码单纯疱疹病毒(HSV)糖蛋白的核苷修饰的mRNA,包括参与病毒进入和免疫逃逸的mRNA,及其使用方法。
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subjects BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
SPIRITS
VINEGAR
WINE
title Modified MRNA vaccine encoding herpes simplex virus glycoprotein and use thereof
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