Composite sheet and medical implant comprising such sheet

Disclosed herein are composite sheets and prosthetic medical devices formed therefrom. In one embodiment, the composite sheet has a thickness of 25 to 250 [mu] m and comprises 10 to 70 mass%, based on the total mass of the composite sheet, of a knitted fabric having a thickness of 15 to 225 [mu] m and comprising 2 to 50 dtex of strands comprising biocompatible polymer fibers, wherein the fabric comprises a thickness in a plurality of first locations, and pores in a plurality of second locations; and 30-90 mass%, based on the total mass of the composite sheet, of a polyurethane coating wherein the polyurethane coating coats the fabric and fills the pores of the fabric such that the composite sheet is substantially water impermeable. 本文公开了复合片材及由其形成的假体医疗设备。在一个实施方式中，复合片材的厚度为25-250μm并且基于所述复合片材的总质量，包含10-70质量％的针织织物，所述针织织物的厚度为15-225μm并且包含2-50dtex的股线，所述股线包含生物相容性聚合物纤维，其中所述织物包含在多个第一位置中的厚度、和在多个第二位置中的孔隙；以及基于所述复合片材的总质量，30-90质量％的聚氨酯涂层，其中所述聚氨酯涂层涂覆所述织物并填充所述织物的所述孔隙，使得所述复合片材基本上不透水。