Inhibitors of MENIN-MLL interaction

The invention relates to an inhibitor of MENIN-MLL interaction, in particular to an inhibitor of interaction of menin, MLL and MLL fusion protein, a pharmaceutical composition containing the inhibitor and application of the inhibitor to treatment of cancers and other diseases mediated by the menin-M...

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Hauptverfasser: LOTESTA STEPHEN D, YUAN JING, DONG CHENGGUO, ZHENG YING, SINGH SURESH B, ZHUANG LINGHANG, JIA LANQI, VENKATRAMAN SUBRAMANIAN, CACATIAN, SALVACION, CLAREMON DAVID A, FAN YI
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creator LOTESTA STEPHEN D
YUAN JING
DONG CHENGGUO
ZHENG YING
SINGH SURESH B
ZHUANG LINGHANG
JIA LANQI
VENKATRAMAN SUBRAMANIAN
CACATIAN, SALVACION
CLAREMON DAVID A
FAN YI
description The invention relates to an inhibitor of MENIN-MLL interaction, in particular to an inhibitor of interaction of menin, MLL and MLL fusion protein, a pharmaceutical composition containing the inhibitor and application of the inhibitor to treatment of cancers and other diseases mediated by the menin-MLL interaction. 本发明涉及MENIN-MLL相互作用的抑制剂,具体涉及menin与MLL及MLL融合蛋白的相互作用的抑制剂、含有该抑制剂的药物组合物及其用于治疗癌症及由menin-MLL相互作用介导的其它疾病的用途。
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Inhibitors of MENIN-MLL interaction
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