Inhibitors of MENIN-MLL interaction

The invention relates to an inhibitor of MENIN-MLL interaction, in particular to an inhibitor of interaction of menin, MLL and MLL fusion protein, a pharmaceutical composition containing the inhibitor and application of the inhibitor to treatment of cancers and other diseases mediated by the menin-M...

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Bibliographische Detailangaben
Hauptverfasser:	LOTESTA STEPHEN D, YUAN JING, DONG CHENGGUO, ZHENG YING, SINGH SURESH B, ZHUANG LINGHANG, JIA LANQI, VENKATRAMAN SUBRAMANIAN, CACATIAN, SALVACION, CLAREMON DAVID A, FAN YI
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to an inhibitor of MENIN-MLL interaction, in particular to an inhibitor of interaction of menin, MLL and MLL fusion protein, a pharmaceutical composition containing the inhibitor and application of the inhibitor to treatment of cancers and other diseases mediated by the menin-MLL interaction. 本发明涉及MENIN-MLL相互作用的抑制剂，具体涉及menin与MLL及MLL融合蛋白的相互作用的抑制剂、含有该抑制剂的药物组合物及其用于治疗癌症及由menin-MLL相互作用介导的其它疾病的用途。