New application of Chinese pulsatilla root decoction in synergistic antibacterial effect of antibiotics
The invention relates to a new application of Chinese pulsatilla root decoction in enhancing antibacterial effects of ceftriaxone, tetracycline and amikacin antibiotics. When the composition or the compound preparation is prepared, the dosage ratio of the Chinese pulsatilla root decoction to the cef...
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| creator | CHEN YIHENG DONG YING LI YONGWEI LIU LANPING XIE MIAO LIU BAOGUANG PANG XIN LIU YALIN XU ERPING JANG JONG-YOON YUAN XIAOLING |
| description | The invention relates to a new application of Chinese pulsatilla root decoction in enhancing antibacterial effects of ceftriaxone, tetracycline and amikacin antibiotics. When the composition or the compound preparation is prepared, the dosage ratio of the Chinese pulsatilla root decoction to the ceftriaxone, the tetracycline and the amikacin is (6400: 1)-(12800: 1). The FIC index of the Chinese pulsatilla root decoction combined with the ceftriaxone, the amikacin or the tetracycline for use is 0.1875-0.375 and is less than 0.5, that is, the Chinese pulsatilla root decoction combined with the ceftriaxone, the amikacin or the tetracycline for use has a synergistic antibacterial effect. The dosage of ceftriaxone, amikacin or tetracycline can be effectively reduced, the MIC value of the Chinese pulsatilla decoction combined with ceftriaxone, amikacin or tetracycline is 2-16 times lower than that of the Chinese pulsatilla decoction independently used, the Chinese pulsatilla decoction can be used as an anti-drug re |
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When the composition or the compound preparation is prepared, the dosage ratio of the Chinese pulsatilla root decoction to the ceftriaxone, the tetracycline and the amikacin is (6400: 1)-(12800: 1). The FIC index of the Chinese pulsatilla root decoction combined with the ceftriaxone, the amikacin or the tetracycline for use is 0.1875-0.375 and is less than 0.5, that is, the Chinese pulsatilla root decoction combined with the ceftriaxone, the amikacin or the tetracycline for use has a synergistic antibacterial effect. 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| subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | New application of Chinese pulsatilla root decoction in synergistic antibacterial effect of antibiotics |
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