Method for producing penicillic acid through penicillium fermentation and application of penicillic acid
The invention discloses a method for producing penicillic acid through penicillium fermentation and application of the penicillic acid, and belongs to the technical field of microbial development and application, the method for producing penicillic acid through penicillium fermentation comprises the...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a method for producing penicillic acid through penicillium fermentation and application of the penicillic acid, and belongs to the technical field of microbial development and application, the method for producing penicillic acid through penicillium fermentation comprises the following steps: S1, inoculating fungi with the preservation number of CGMCC No.41147 into a liquid fermentation culture medium, and carrying out shaking fermentation culture for 10 days in a shaking table at 28 DEG C to obtain a fermentation crude product; s2, the fermentation supernatant is extracted through ethyl acetate, a crude extract is obtained through reduced pressure distillation, the penicillic acid monomer is obtained through separation and purification by means of chromatography, compared with a conventional fungus for producing penicillic acid, the yield of the penicillic acid produced by the fungus is increased by about 2-3 times, and when the fungus is applied to large-scale production of the penic |
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