Inhibitor targeting RIPK1 kinase and application thereof

The invention discloses an inhibitor targeting RIPK1 kinase and application of the inhibitor. The inhibitor targeting RIPK1 kinase is selected from a compound with a structure shown as a general formula (I) or (II) or pharmaceutically acceptable salt of the compound. The invention provides a series of novel kinase targeted inhibitors, and the compound disclosed by the invention can effectively target RIPK1 kinase and can be used as an effective therapeutic agent for inflammation-related diseases. 本发明公开了一类靶向RIPK1激酶的抑制剂及其应用，所述的靶向RIPK1激酶的抑制剂选自结构如通式(Ⅰ)或(II)所示的化合物或其药学上可接受的盐。本发明提供了一系列新型的激酶靶向抑制剂，本发明所公示化合物能够有效的靶向RIPK1激酶，可作为炎症相关疾病的有效治疗剂。