Combinations of KRAS G12D inhibitors with PI3Ka inhibitors and related therapeutic methods

The present invention relates to a combination therapy for the treatment of KRas G12D cancer; specifically, the present invention relates to a method of treating cancer in a subject in need thereof, the method comprising administering to the subject a therapeutically effective amount of a combination of a PI3Ka inhibitor and a KRas G12D inhibitor, pharmaceutical compositions comprising such compositions, kits comprising such compositions, and methods of use thereof. 本发明涉及用于治疗KRas G12D癌症的组合疗法；具体地，本发明涉及治疗有需要的受试者的癌症的方法，所述方法包括向所述受试者施用治疗有效量的PI3Ka抑制剂与KRas G12D抑制剂的组合，包含此类组合物的药物组合物、包括此类组合物的药盒及其使用方法。