SOLID FORMS COMPRISING OXOISOINDOLE COMPOUNDS AND SALTS THEREOF, AND COMPOSITIONS COMPRISING SAME AND METHODS OF THEIR USE
Provided herein are formulations, processes, solid forms, and methods of use that relate to salts of (S)-4-(4-(((2-(2, 6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl) oxy) methyl) benzyl) piperazin-1-yl)-3-fluorobenzonitrile and compositions comprising (S)-4-(4-(((2-(2, 6-dioxopiperidin-3-yl)-1-oxoisoi...
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| creator | FERRETTI ANTONIO C HUANG LIANFENG WU WENJU ARTMAN III GERALD D YIN ZHIWEI TAVARES-GRECO PAULA A ZOU NANCY NIEHUA JAIN, UDAY KUMAR MAN HON-WAH |
| description | Provided herein are formulations, processes, solid forms, and methods of use that relate to salts of (S)-4-(4-(((2-(2, 6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl) oxy) methyl) benzyl) piperazin-1-yl)-3-fluorobenzonitrile and compositions comprising (S)-4-(4-(((2-(2, 6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl) methyl) piperazin-1-yl)-3-fluorobenzonitrile and salts of (S)-4-(4-(((2-(2, 6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)-3-fluorobenzonitrile. The present invention relates to a solid form of a free base or salt of 2, 6-dioxopiperidine-3-yl)-1-oxoisoindolin-4-yl) oxy) methyl) benzyl) piperazin-1-yl)-3-fluorobenzonitrile.
本文提供了配方、工艺、固体形式和使用方法，它们涉及(S)-4-(4-(4-(((2-(2，6-二氧代哌啶-3-基)-1-氧代异吲哚啉-4-基)氧基)甲基)苯甲基)哌嗪-1-基)-3-氟苯甲腈的盐以及包含(S)-4-(4-(4-(((2-(2，6-二氧代哌啶-3-基)-1-氧代异吲哚啉-4-基)氧基)甲基)苯甲基)哌嗪-1-基)-3-氟苯甲腈的游离碱或盐的固体形式。 |
| format | Patent |
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本文提供了配方、工艺、固体形式和使用方法，它们涉及(S)-4-(4-(4-(((2-(2，6-二氧代哌啶-3-基)-1-氧代异吲哚啉-4-基)氧基)甲基)苯甲基)哌嗪-1-基)-3-氟苯甲腈的盐以及包含(S)-4-(4-(4-(((2-(2，6-二氧代哌啶-3-基)-1-氧代异吲哚啉-4-基)氧基)甲基)苯甲基)哌嗪-1-基)-3-氟苯甲腈的游离碱或盐的固体形式。</description><language>chi ; eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240712&DB=EPODOC&CC=CN&NR=118324742A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25562,76317</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240712&DB=EPODOC&CC=CN&NR=118324742A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>FERRETTI ANTONIO C</creatorcontrib><creatorcontrib>HUANG LIANFENG</creatorcontrib><creatorcontrib>WU WENJU</creatorcontrib><creatorcontrib>ARTMAN III GERALD D</creatorcontrib><creatorcontrib>YIN ZHIWEI</creatorcontrib><creatorcontrib>TAVARES-GRECO PAULA A</creatorcontrib><creatorcontrib>ZOU NANCY NIEHUA</creatorcontrib><creatorcontrib>JAIN, UDAY KUMAR</creatorcontrib><creatorcontrib>MAN HON-WAH</creatorcontrib><title>SOLID FORMS COMPRISING OXOISOINDOLE COMPOUNDS AND SALTS THEREOF, AND COMPOSITIONS COMPRISING SAME AND METHODS OF THEIR USE</title><description>Provided herein are formulations, processes, solid forms, and methods of use that relate to salts of (S)-4-(4-(((2-(2, 6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl) oxy) methyl) benzyl) piperazin-1-yl)-3-fluorobenzonitrile and compositions comprising (S)-4-(4-(((2-(2, 6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl) methyl) piperazin-1-yl)-3-fluorobenzonitrile and salts of (S)-4-(4-(((2-(2, 6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)-3-fluorobenzonitrile. The present invention relates to a solid form of a free base or salt of 2, 6-dioxopiperidine-3-yl)-1-oxoisoindolin-4-yl) oxy) methyl) benzyl) piperazin-1-yl)-3-fluorobenzonitrile.
本文提供了配方、工艺、固体形式和使用方法，它们涉及(S)-4-(4-(4-(((2-(2，6-二氧代哌啶-3-基)-1-氧代异吲哚啉-4-基)氧基)甲基)苯甲基)哌嗪-1-基)-3-氟苯甲腈的盐以及包含(S)-4-(4-(4-(((2-(2，6-二氧代哌啶-3-基)-1-氧代异吲哚啉-4-基)氧基)甲基)苯甲基)哌嗪-1-基)-3-氟苯甲腈的游离碱或盐的固体形式。</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjL0KwjAURrs4iPoO112H_oCuobmxF5pcyU3BrRSJk2ihTj69GlzcnD44nPPNs6dwSxoMeytQsz16EnIH4BOTMDnNLSbOndMCymkQ1QaB0KBHNpuEkiAUiN3PiyiLSbAYGn73bD4heegEl9nsMlynuPruIlsbDHWzjeO9j9M4nOMtPvra5fm-LKpdVajyH-cFR6o6xQ</recordid><startdate>20240712</startdate><enddate>20240712</enddate><creator>FERRETTI ANTONIO C</creator><creator>HUANG LIANFENG</creator><creator>WU WENJU</creator><creator>ARTMAN III GERALD D</creator><creator>YIN ZHIWEI</creator><creator>TAVARES-GRECO PAULA A</creator><creator>ZOU NANCY NIEHUA</creator><creator>JAIN, UDAY KUMAR</creator><creator>MAN HON-WAH</creator><scope>EVB</scope></search><sort><creationdate>20240712</creationdate><title>SOLID FORMS COMPRISING OXOISOINDOLE COMPOUNDS AND SALTS THEREOF, AND COMPOSITIONS COMPRISING SAME AND METHODS OF THEIR USE</title><author>FERRETTI ANTONIO C ; HUANG LIANFENG ; WU WENJU ; ARTMAN III GERALD D ; YIN ZHIWEI ; TAVARES-GRECO PAULA A ; ZOU NANCY NIEHUA ; JAIN, UDAY KUMAR ; MAN HON-WAH</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN118324742A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2024</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>FERRETTI ANTONIO C</creatorcontrib><creatorcontrib>HUANG LIANFENG</creatorcontrib><creatorcontrib>WU WENJU</creatorcontrib><creatorcontrib>ARTMAN III GERALD D</creatorcontrib><creatorcontrib>YIN ZHIWEI</creatorcontrib><creatorcontrib>TAVARES-GRECO PAULA A</creatorcontrib><creatorcontrib>ZOU NANCY NIEHUA</creatorcontrib><creatorcontrib>JAIN, UDAY KUMAR</creatorcontrib><creatorcontrib>MAN HON-WAH</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>FERRETTI ANTONIO C</au><au>HUANG LIANFENG</au><au>WU WENJU</au><au>ARTMAN III GERALD D</au><au>YIN ZHIWEI</au><au>TAVARES-GRECO PAULA A</au><au>ZOU NANCY NIEHUA</au><au>JAIN, UDAY KUMAR</au><au>MAN HON-WAH</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>SOLID FORMS COMPRISING OXOISOINDOLE COMPOUNDS AND SALTS THEREOF, AND COMPOSITIONS COMPRISING SAME AND METHODS OF THEIR USE</title><date>2024-07-12</date><risdate>2024</risdate><abstract>Provided herein are formulations, processes, solid forms, and methods of use that relate to salts of (S)-4-(4-(((2-(2, 6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl) oxy) methyl) benzyl) piperazin-1-yl)-3-fluorobenzonitrile and compositions comprising (S)-4-(4-(((2-(2, 6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl) methyl) piperazin-1-yl)-3-fluorobenzonitrile and salts of (S)-4-(4-(((2-(2, 6-dioxopiperidin-3-yl)-1-oxoisoindolin-4-yl)-3-fluorobenzonitrile. The present invention relates to a solid form of a free base or salt of 2, 6-dioxopiperidine-3-yl)-1-oxoisoindolin-4-yl) oxy) methyl) benzyl) piperazin-1-yl)-3-fluorobenzonitrile.
本文提供了配方、工艺、固体形式和使用方法，它们涉及(S)-4-(4-(4-(((2-(2，6-二氧代哌啶-3-基)-1-氧代异吲哚啉-4-基)氧基)甲基)苯甲基)哌嗪-1-基)-3-氟苯甲腈的盐以及包含(S)-4-(4-(4-(((2-(2，6-二氧代哌啶-3-基)-1-氧代异吲哚啉-4-基)氧基)甲基)苯甲基)哌嗪-1-基)-3-氟苯甲腈的游离碱或盐的固体形式。</abstract><oa>free_for_read</oa></addata></record> |
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| title | SOLID FORMS COMPRISING OXOISOINDOLE COMPOUNDS AND SALTS THEREOF, AND COMPOSITIONS COMPRISING SAME AND METHODS OF THEIR USE |
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