Method for checking and accepting water for mass spectrometric detection of metronidazole and chloramphenicol

The invention provides a method for checking and accepting water for metronidazole and chloramphenicol mass spectrometric detection, and belongs to the technical field of drug detection. The invention relates to a method for checking and accepting water for metronidazole and chloramphenicol mass spe...

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Hauptverfasser: ZHU QIONG, QIAN ZHONGYI, QIAN XIAOCUI, BAI DAWEI, JIANG JING, GAO DEHUA, XIONG HUAN, FANG JING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a method for checking and accepting water for metronidazole and chloramphenicol mass spectrometric detection, and belongs to the technical field of drug detection. The invention relates to a method for checking and accepting water for metronidazole and chloramphenicol mass spectrometric detection. The method comprises a series of steps of visual observation, accurate determination, preparation of a reference solution, determination of a detection limit, determination of water sample applicability and the like. By means of refining and expanding the quality requirement of the water for mass spectrum detection, establishing an acceptance method of a specific substance, introducing a blank solution contrast experiment and the like, on one hand, the water for mass spectrum detection is more comprehensive on the basis of the existing acceptance standard, and the quality monitoring is more perfect; on the other hand, result deviation caused by mistaken selection of experimental water is effec