Rhodium/inorganic iodide catalyst system for methanol carbonylation process with improved impurity profile

本发明的方法提供了显著减少羰基杂质形成、与现有技术甲醇羰基化方法相比的改进。已经发现，羰基杂质，尤其乙醛、巴豆醛和2-乙基巴豆醛在甲醇羰基化反应中的形成通过在反应过程中使甲基碘在反应介质中保持大约5wt％或5wt％以下得到降低。 The method of the present invention provides an improvement upon prior art methanol carbonylation methods which substantially reduces the production of carbonyl impurities.The production of carbonyl impurities, particularly acetaldehyde, crotonaldehyde, and 2-ethyl crotonaldehyde, in methanol carbonylation reactions has been found to decrease by maintaining less than about 4.5 wt % methyl iodide in the reaction medium during the course of the reaction.