Heterocyclic derivative containing quinazolinone pyrrolidone unit as well as preparation method and application of heterocyclic derivative

The invention provides a heterocyclic derivative containing a quinazolinone and pyrrolidone unit as well as a preparation method and application of the heterocyclic derivative. The structural formula of the heterocyclic derivative containing the quinazolinone and pyrrolidone unit is # imgabs0. The preparation method of the heterocyclic derivative containing the quinazolinone and pyrrolidone unit comprises the following steps: starting from simple and easily available raw materials, and carrying out two-step reaction to obtain the polysubstituted heterocyclic derivative of a natural quinazolinone and pyrrolidone skeleton. The heterocyclic derivative provided by the invention has good antiviral activity and a novel structure, and can be used as a main component of an antiviral drug for preparing a novel antiviral drug. 本发明提供了一种含喹唑啉酮并吡咯烷酮单元的杂环衍生物及制备方法和应用。本发明的含喹唑啉酮并吡咯烷酮单元的杂环衍生物，结构式为#imgabs0#本发明的含喹唑啉酮并吡咯烷酮单元的杂环衍生物的制备方法，由简单易得的原料出发，经过两步反应即得到天然喹唑啉酮并吡咯烷酮骨架的多取代杂环衍生物。本发明提供的杂环衍生物具有很好的抗病毒活性，且结构新颖，可作为抗病毒药物的主要成分用于制备新型抗病毒药物。