Intramedullary nail containing drug coating and preparation method of intramedullary nail

The invention belongs to the technical field of medical instruments, and particularly relates to an intramedullary nail containing a drug coating and a preparation method of the intramedullary nail. The intramedullary nail containing the drug coating comprises a titanium alloy intramedullary nail ba...

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Bibliographische Detailangaben
Hauptverfasser: YUE ZHONGBO, CHANG RENCAO, ZHANG LICHUANG, ZHAO XUANCHENG
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention belongs to the technical field of medical instruments, and particularly relates to an intramedullary nail containing a drug coating and a preparation method of the intramedullary nail. The intramedullary nail containing the drug coating comprises a titanium alloy intramedullary nail base body, a porous film layer and the drug-loaded microsphere coating, wherein the porous film layer and the drug-loaded microsphere coating are arranged on the surface of the base body. According to the intramedullary nail containing the drug coating, the titanium alloy matrix is subjected to surface treatment, the polymer microspheres are used as a carrier to form the drug coating, the intramedullary nail has the advantages that operation is easy, the dosage is easy to control, the binding force is higher than that of a traditional surface coating, and the drug slow release capacity is improved. 本发明属于医疗器械技术领域,具体涉及一种含药物涂层的髓内钉及其制备方法。本发明所述含药物涂层的髓内钉,包括钛合金髓内钉基体和设置于基体表面的多孔薄膜层和载药微球涂层。本发明所述含药物涂层的髓内钉,通过对钛合金基体进行表面处理,并使用聚合物微