Newcastle disease inactivated vaccine for pigeons

The invention belongs to the technical field of biology, and discloses a pigeon Newcastle disease inactivated vaccine which comprises an oil phase and a water phase, the water phase contains an antigen solution and tween-80; the antigen liquid is inactivated pigeon Newcastle disease venom; the conce...

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Hauptverfasser: TU YURONG, HE LIUFEN, ZHENG QIAOWEI, LI JING, QI DONGMEI, WANG WEI, WANG QIANJU, HU MEIRONG, LI YONGHONG, HAN FEI, TONG JUYUN, ZHENG TIESUO, ZHONG ZHIWEN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of biology, and discloses a pigeon Newcastle disease inactivated vaccine which comprises an oil phase and a water phase, the water phase contains an antigen solution and tween-80; the antigen liquid is inactivated pigeon Newcastle disease venom; the concentration of the tween-80 in the water phase is 0.5 vol% to 1.0 vol%. According to the vaccine, after the Tween-80 in the water phase is reduced to 1.0 vol% or below of the total volume of the water phase, the safety and effectiveness of the prepared vaccine are obviously improved. 本发明属于生物技术领域,公开了一种鸽新城疫灭活疫苗,包括油相和水相;所述水相中含有抗原液、吐温-80;所述抗原液为灭活的鸽新城疫病毒液;所述吐温-80在水相中浓度为0.5vol%~1.0vol%。该疫苗将水相中的吐温-80降低到水相总体积的1.0vol%以下后,所制备的疫苗安全性和有效性均明显提高。