Enhancer of TCR clone number

The present invention provides a TCR clone number enhancer comprising a viable lactic acid bacterium as an active ingredient. Provided is an enhancer for the number of TCR clones, which is characterized in that the number of TCR clones having TRBV19 is increased after vaccination of a vaccine having...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	NAITO TOMOAKI, HORI TETSUJI, TAJIMA SAYA, MATSUMOTO SATOSHI, MAKI IKUFU
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The present invention provides a TCR clone number enhancer comprising a viable lactic acid bacterium as an active ingredient. Provided is an enhancer for the number of TCR clones, which is characterized in that the number of TCR clones having TRBV19 is increased after vaccination of a vaccine having a virus having an epitope recognized by CD4 or CD8 positive T cells of TRBV19, such as an IFV vaccine, using a viable bacterium of a lactic acid bacterium as an active ingredient. 本发明提供以乳酸菌的活菌为有效成分的TCR克隆数的增强剂。本发明提供TCR克隆数的增强剂，其特征在于，以乳酸菌的活菌为有效成分，在接种IFV的疫苗等具有被持有TRBV19的CD4、或CD8阳性T细胞识别的表位的病毒的疫苗后，增强具有TRBV19的TCR克隆数。