Key marker-based depression detection reagent, detection system and application thereof

The invention discloses a key marker-based depression detection reagent, a key marker-based depression detection system and application thereof. The depression detection reagent combination based on the key marker comprises a calibrator of a to-be-detected compound serving as a biomarker, a quality...

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Hauptverfasser: SHENG PIJIE, ZHOU YUE, LI SIJIA, YUAN YONGGUI, ZHU JUAN, PENG JUN, SUN TAIPENG, WANG ZHENGYANG, CAO SHANSHAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a key marker-based depression detection reagent, a key marker-based depression detection system and application thereof. The depression detection reagent combination based on the key marker comprises a calibrator of a to-be-detected compound serving as a biomarker, a quality control product and an extracting solution, wherein the compound to be detected is 3-hydroxy o-aminobenzoic acid and any 2-5 compounds selected from the group consisting of 5-hydroxy o-aminobenzoic acid, phenyl acetate, gamma-aminobutyric acid, 3, 4-dihydroxy phenylacetic acid, 2-picolinic acid, quinolinic acid, kynurenine, 5-hydroxytryptophan, 3-hydroxy kynurenine and glycocholic acid. According to the reagent combination and the detection system, the diagnosis accuracy can be remarkably improved, the detection is convenient, the repeatability of detection data is good, the specificity is high, and the clinical diagnosis result is accurate. 一种基于关键标志物的抑郁症检测试剂、检测系统及其应用。所述基于关键标志物的抑郁症检测试剂组合,包括作为生物标记物的待检测化合物的校准品、质控品和提取