Dacarbazin-specific terbium-containing nano-micelle in-situ sensing material, method and application

The invention discloses a dacarbazin-specific terbium-containing nano-micelle in-situ sensing material and a method and application thereof, sodium hyaluronate (HA) is prepared into an aqueous solution with the concentration of 0.2-6 mg/mL by using an acetic acid buffer solution with the pH value of 4-9, the prepared sodium hyaluronate aqueous solution is dropwise added into a prepared terbium complex ethanol solution according to a proper volume ratio, and the terbium-containing nano-micelle in-situ sensing material is obtained after the terbium-containing nano-micelle in-situ sensing material is prepared. And fully stirring for 30-120 minutes at the temperature of 5-40 DEG C at the speed of 2000-10000 rmp until uniformly dispersed micelles are formed, centrifuging at a high speed, and slowly washing with sterile distilled water to obtain the terbium-containing nano-micelle in-situ sensing material specific to dacarbazin. The nano-micelle in-situ drug sensing material is formed by self-assembly of a novel te