Unsaturated six-membered heterocycle substituted aryl sulfonyl pyrrole derivative and application thereof

The invention discloses an unsaturated six-membered heterocycle substituted aryl sulfonyl pyrrole derivative and application thereof, and discloses a compound shown in a general formula (I) or a tautomer, an enantiomer, a diastereoisomer, a mixture and pharmaceutically acceptable salt thereof, # imgabs0 #, wherein X1 and X2 are independently selected from C or N; x1 and X2 may be the same as or different from each other; y is selected from O, S, NH and SO2; r is selected from H or F. 非饱和六元杂环取代的芳基磺酰吡咯类衍生物及应用，本发明公开通式(I)所示的化合物或其互变异构体、对映异构体、非对映异构体、混合物、及其药学上可接受的盐，#imgabs0#其中：X1和X2独立地选自C或者N；X1和X2可以相同也可以不同；Y选自O、S、NH、SO2；R选自H或者F。