Continuous production method and device of 2-methyl-4-chlorophenoxyacetic acid intermediate

The invention relates to the technical field of pesticide preparation, and discloses a continuous production method and device of a 2-methyl-4-chlorophenoxyacetic acid intermediate. The method comprises the following step: in the presence of a chlorinated solvent and a catalyst, carrying out continu...

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Bibliographische Detailangaben
Hauptverfasser: LI ZHIQING, XU FEN, ZHANG XIAOFEI, YIN ZHUOLIN, ZHOU CHANGTAO, HAN FUJUN, HU YISHAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to the technical field of pesticide preparation, and discloses a continuous production method and device of a 2-methyl-4-chlorophenoxyacetic acid intermediate. The method comprises the following step: in the presence of a chlorinated solvent and a catalyst, carrying out continuous reaction on o-cresol and sulfuryl chloride at the temperature of 5 DEG C below zero to 5 DEG C to obtain the 2-methyl-4-chlorophenol. The continuous production device comprises a tubular or micro-channel reactor, a plate type reactor, a climbing film reactor and a falling film reactor which are sequentially connected in series. The synthetic reaction conditions of the intermediate 2-methyl-4-chlorophenol of the 2-methyl-4-chlorophenoxyacetic acid are improved by a solvent method, the freezing points of the raw material o-cresol and the product 2-methyl-4-chlorophenol are reduced, the reaction liquid is maintained in a homogeneous state, the reaction temperature is further controlled, and the yield of the 2-meth