Methods of treating ocular inflammatory diseases

The present invention relates to methods of treating ocular inflammatory diseases by administering an ophthalmic pharmaceutical composition of roflumilast. The ophthalmic pharmaceutical composition for administering roflumilast can provide significant immunomodulatory and anti-inflammatory activity,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: HERMATI HAROUN D, ESTES DAVID J, JEFFORDS ERIC W, GUCASSIAN, HECTOR, J, VERHOEVEN, ROBERT
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention relates to methods of treating ocular inflammatory diseases by administering an ophthalmic pharmaceutical composition of roflumilast. The ophthalmic pharmaceutical composition for administering roflumilast can provide significant immunomodulatory and anti-inflammatory activity, while also providing improved safety and convenience relative to the one or both of these agents, over existing immunomodulatory agents, immunosuppressive agents, or non-steroidal anti-inflammatory therapeutic agents, including corticosteroids and antihistamine agents. 本发明涉及通过施用罗氟司特的眼用药物组合物来治疗眼部炎性疾病的方法。相对于现有的免疫调节剂、免疫抑制剂或非甾体抗炎治疗剂(包括皮质类固醇和抗组胺剂),施用罗氟司特的眼用药物组合物能够提供显著的免疫调节和抗炎活性,同时相对于这一种或两种药剂还提供改善的安全性和便利性。