Medical application of CD74

The invention belongs to the field of biological medicine, and relates to medical application of CD74. Specifically, the invention relates to a CD74 protein or a representative fragment thereof, a nucleic acid molecule for coding the CD74 protein or the representative fragment thereof, a reagent for...

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Bibliographische Detailangaben
Hauptverfasser:	WANG JIANGHUA, XIAO GUANXI, XIA YU, LI BAIYONG
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention belongs to the field of biological medicine, and relates to medical application of CD74. Specifically, the invention relates to a CD74 protein or a representative fragment thereof, a nucleic acid molecule for coding the CD74 protein or the representative fragment thereof, a reagent for detecting the CD74 protein or the representative fragment thereof, or application of the reagent for detecting the nucleic acid molecule for coding the CD74 protein or the representative fragment thereof in preparation of a medicine for predicting the effect of an anti-tumor medicine on treating tumor of a subject. CD74 can be used as a biomarker for predicting the tumor treatment effect, and has a good application prospect. 本发明属于生物医药领域，涉及CD74的医药用途。具体地，本发明涉及CD74蛋白或其代表性片段、编码CD74蛋白或其代表性片段的核酸分子、检测CD74蛋白或其代表性片段的试剂、或者检测编码CD74蛋白或其代表性片段的核酸分子的试剂在制备用于预测抗肿瘤药物治疗受试者肿瘤的效果的药物中的用途。CD74能够作为预测治疗肿瘤的效果的生物标志物，具有良好的应用前景。