Granules obtainable by continuous melt granulation

The present invention relates to water-soluble or water-dispersible particles obtainable by continuous melt granulation. The particles comprise at least one binder, at least one filler and at least one active ingredient. Torque overload may be avoided when using a combination of a filler (e.g., mann...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BEKAERT BRAM, POTTIER CHRISTOPHE, VAN DER WIEL, LISE, VIEVART CHRIS
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention relates to water-soluble or water-dispersible particles obtainable by continuous melt granulation. The particles comprise at least one binder, at least one filler and at least one active ingredient. Torque overload may be avoided when using a combination of a filler (e.g., mannitol or HMO) and a binder (e.g., sorbitol) disclosed herein. 本发明涉及可通过连续熔融造粒获得的水溶性或水分散性颗粒。颗粒包含至少一种粘结剂、至少一种填充剂和至少一种活性成分。在使用本文公开的填充剂(例如甘露糖醇或HMO)和粘结剂(例如山梨糖醇)的组合时可避免扭矩过载。