Hydroxypropyl methyl cellulose shading empty capsule and preparation method thereof

The invention provides a hydroxypropyl methyl cellulose shading empty capsule and a preparation method thereof, the empty capsule comprises the following components: hydroxypropyl methyl cellulose, a gelling agent, a coagulation accelerator, a calcium salt and a reinforcing agent, and the reinforcing agent comprises a phospholipid compound. The phospholipid compound and the hydroxypropyl methyl cellulose form a compound, so that the interaction between calcium ions and the hydroxypropyl methyl cellulose can be physically blocked, and the damage of calcium salt to the structure of the cellulose is reduced. Meanwhile, a hydrophilic head group and a hydrophobic group in phospholipid molecules interact with groups in the hydroxypropyl methyl cellulose, so that the combination of the phospholipid and the cellulose is enhanced, and the damage of calcium salt to the cellulose is reduced. 本发明提出了一种羟丙基甲基纤维素遮光空心胶囊及其制备方法，所述空心胶囊包括以下组分：羟丙基甲基纤维素、凝胶剂、促凝剂、钙盐和增强剂，所述增强剂包括磷脂类化合物。磷脂类化合物与羟丙基甲基纤维素形成复合物，可以在物理上阻隔钙离子与羟丙基甲基纤维素之间的相互作用，减