Method for multi-modal identification of conversion from anxiety disorder to cognitive dysfunction

The invention discloses a method for multi-modal recognition of conversion from anxiety disorder to cognitive impairment, which depends on Shanghai senile brain health (SHBAS) queues, collects the characteristic data, divides incorporated individuals into cognitive stability and cognitive decline according to cognitive follow-up visit conditions, adopts LASSO (lasso algorithm) to screen variables, and determines the conversion from anxiety disorder to cognitive impairment. Area under the curve (AUC) is used as an evaluation index, and the established model is verified in an external data British Biological Bank (UKB), so that screening of anxiety disorder cognitive impairment individuals which can be popularized in the aged of a community is established, early intervention and treatment are performed, and the burden of the society and families is reduced. 本发明公开了一种多模态识别焦虑障碍向认知功能障碍转化的方法，该方法依托上海老年脑健康(SHBAS)队列，采集以上特征数据，根据认知随访情况，将纳入个体分为认知稳定和认知下降两类，采用套索算法(LASSO)筛选变量，根据曲线下面积(AUC)作为评估指标，建立的模型在外部数据英国生物库(UKB)中进行验证，从而建立