Antibacterial lubricating double-layer polymer brush coating as well as preparation method and application thereof

The invention discloses an antibacterial lubricating double-layer polymer brush coating and a preparation method and application thereof, and relates to the technical field of medical catheter surface modification.The preparation method comprises the steps that a medical catheter is soaked in an alc...

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Bibliographische Detailangaben
Hauptverfasser: HONG RUI, WANG ZHIGUO, GOU JUXIANG, ZHAO BAISONG, WEI YUQING, XU JIAZHUANG, WANG JUNYANG, LI ZHONGMING
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses an antibacterial lubricating double-layer polymer brush coating and a preparation method and application thereof, and relates to the technical field of medical catheter surface modification.The preparation method comprises the steps that a medical catheter is soaked in an alcoholic solution containing a hydrophobic photoinitiator and a hydrophobic thermal initiator, and the treated medical catheter is obtained; dissolving a hydrophilic polymer brush monomer and a hydrophilic thermal initiator in water to form a first mixed solution; dissolving an antibacterial agent monomer and a hydrophilic thermal initiator in water to form a second mixed solution; the treated medical catheter is placed in a first mixed solution to be subjected to illumination heating, and a first antibacterial lubricating polymer brush coating layer is obtained; and heating the first antibacterial lubricating polymer brush coating layer in the second mixed solution to obtain a second antibacterial lubricating polyme