Probe combination, kit and method for detecting genetic susceptibility genes of ovarian cancer
The invention discloses a probe combination for detecting an ovarian cancer genetic susceptibility gene. The probe combination comprises at least one of sequences as shown in SEQ ID NO 1-641. The invention also discloses a kit comprising the probe combination and a method for detecting the genetic s...
Gespeichert in:
| Hauptverfasser: | , , , , , |
|---|---|
| Format: | Patent |
| Sprache: | chi ; eng |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | YU KE HE PENGHAI LIN XIAOJIAN MA YINI HU YAOWEN DING LINFENG |
| description | The invention discloses a probe combination for detecting an ovarian cancer genetic susceptibility gene. The probe combination comprises at least one of sequences as shown in SEQ ID NO 1-641. The invention also discloses a kit comprising the probe combination and a method for detecting the genetic susceptibility gene of the ovarian cancer by using the kit. According to the present invention, the ovarian cancer genetic susceptibility related genes such as ATM, BRCA1, BRCA2, BRIP1, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, PTEN, RAD51C, RAD51D and STK11 can be detected at one time by using the hybrid capture method; the probe is wide in coverage, high in sequencing depth and capable of detecting embryonic line variation of all exon regions of a target gene. According to the invention, all related diseases of ovarian cancer genetic susceptibility related genes can be reported, and genetic modes corresponding to the diseases are provided.
本发明公开了一种检测卵巢癌遗传易感基因的探针组合，包括SEQ ID NO 1～641所示序列中的至少一种。并公开了包括所述探针组合的试剂盒以及利用所述试剂盒检 |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CN118222705A</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CN118222705A</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CN118222705A3</originalsourceid><addsrcrecordid>eNqNjLEKwlAMALs4iPoPcVewFamrFMVJHJwtaZrWYJuU96Lg34viBzgdHMeNk-s5WMVA1lei6GK6gLs4oNbQs9-shsYC1OxMLtpCy8ouBPERiQeXSjrx11dHsAbsiUFQgVCJwzQZNdhFnv04SeaH_aU4LnmwkuOA9NmVxSlNt1mW5avNbv1P8wYxPTyN</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Probe combination, kit and method for detecting genetic susceptibility genes of ovarian cancer</title><source>esp@cenet</source><creator>YU KE ; HE PENGHAI ; LIN XIAOJIAN ; MA YINI ; HU YAOWEN ; DING LINFENG</creator><creatorcontrib>YU KE ; HE PENGHAI ; LIN XIAOJIAN ; MA YINI ; HU YAOWEN ; DING LINFENG</creatorcontrib><description>The invention discloses a probe combination for detecting an ovarian cancer genetic susceptibility gene. The probe combination comprises at least one of sequences as shown in SEQ ID NO 1-641. The invention also discloses a kit comprising the probe combination and a method for detecting the genetic susceptibility gene of the ovarian cancer by using the kit. According to the present invention, the ovarian cancer genetic susceptibility related genes such as ATM, BRCA1, BRCA2, BRIP1, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, PTEN, RAD51C, RAD51D and STK11 can be detected at one time by using the hybrid capture method; the probe is wide in coverage, high in sequencing depth and capable of detecting embryonic line variation of all exon regions of a target gene. According to the invention, all related diseases of ovarian cancer genetic susceptibility related genes can be reported, and genetic modes corresponding to the diseases are provided.
本发明公开了一种检测卵巢癌遗传易感基因的探针组合，包括SEQ ID NO 1～641所示序列中的至少一种。并公开了包括所述探针组合的试剂盒以及利用所述试剂盒检</description><language>chi ; eng</language><subject>BEER ; BIOCHEMISTRY ; CHEMISTRY ; COMBINATORIAL CHEMISTRY ; COMPOSITIONS OR TEST PAPERS THEREFOR ; COMPOSITIONS THEREOF ; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ; CULTURE MEDIA ; ENZYMOLOGY ; LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES ; MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS ; METALLURGY ; MICROBIOLOGY ; MICROORGANISMS OR ENZYMES ; MUTATION OR GENETIC ENGINEERING ; PROCESSES OF PREPARING SUCH COMPOSITIONS ; PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS ; SPIRITS ; VINEGAR ; WINE</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240621&DB=EPODOC&CC=CN&NR=118222705A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240621&DB=EPODOC&CC=CN&NR=118222705A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>YU KE</creatorcontrib><creatorcontrib>HE PENGHAI</creatorcontrib><creatorcontrib>LIN XIAOJIAN</creatorcontrib><creatorcontrib>MA YINI</creatorcontrib><creatorcontrib>HU YAOWEN</creatorcontrib><creatorcontrib>DING LINFENG</creatorcontrib><title>Probe combination, kit and method for detecting genetic susceptibility genes of ovarian cancer</title><description>The invention discloses a probe combination for detecting an ovarian cancer genetic susceptibility gene. The probe combination comprises at least one of sequences as shown in SEQ ID NO 1-641. The invention also discloses a kit comprising the probe combination and a method for detecting the genetic susceptibility gene of the ovarian cancer by using the kit. According to the present invention, the ovarian cancer genetic susceptibility related genes such as ATM, BRCA1, BRCA2, BRIP1, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, PTEN, RAD51C, RAD51D and STK11 can be detected at one time by using the hybrid capture method; the probe is wide in coverage, high in sequencing depth and capable of detecting embryonic line variation of all exon regions of a target gene. According to the invention, all related diseases of ovarian cancer genetic susceptibility related genes can be reported, and genetic modes corresponding to the diseases are provided.
本发明公开了一种检测卵巢癌遗传易感基因的探针组合，包括SEQ ID NO 1～641所示序列中的至少一种。并公开了包括所述探针组合的试剂盒以及利用所述试剂盒检</description><subject>BEER</subject><subject>BIOCHEMISTRY</subject><subject>CHEMISTRY</subject><subject>COMBINATORIAL CHEMISTRY</subject><subject>COMPOSITIONS OR TEST PAPERS THEREFOR</subject><subject>COMPOSITIONS THEREOF</subject><subject>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</subject><subject>CULTURE MEDIA</subject><subject>ENZYMOLOGY</subject><subject>LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES</subject><subject>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</subject><subject>METALLURGY</subject><subject>MICROBIOLOGY</subject><subject>MICROORGANISMS OR ENZYMES</subject><subject>MUTATION OR GENETIC ENGINEERING</subject><subject>PROCESSES OF PREPARING SUCH COMPOSITIONS</subject><subject>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</subject><subject>SPIRITS</subject><subject>VINEGAR</subject><subject>WINE</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2024</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjLEKwlAMALs4iPoPcVewFamrFMVJHJwtaZrWYJuU96Lg34viBzgdHMeNk-s5WMVA1lei6GK6gLs4oNbQs9-shsYC1OxMLtpCy8ouBPERiQeXSjrx11dHsAbsiUFQgVCJwzQZNdhFnv04SeaH_aU4LnmwkuOA9NmVxSlNt1mW5avNbv1P8wYxPTyN</recordid><startdate>20240621</startdate><enddate>20240621</enddate><creator>YU KE</creator><creator>HE PENGHAI</creator><creator>LIN XIAOJIAN</creator><creator>MA YINI</creator><creator>HU YAOWEN</creator><creator>DING LINFENG</creator><scope>EVB</scope></search><sort><creationdate>20240621</creationdate><title>Probe combination, kit and method for detecting genetic susceptibility genes of ovarian cancer</title><author>YU KE ; HE PENGHAI ; LIN XIAOJIAN ; MA YINI ; HU YAOWEN ; DING LINFENG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CN118222705A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>chi ; eng</language><creationdate>2024</creationdate><topic>BEER</topic><topic>BIOCHEMISTRY</topic><topic>CHEMISTRY</topic><topic>COMBINATORIAL CHEMISTRY</topic><topic>COMPOSITIONS OR TEST PAPERS THEREFOR</topic><topic>COMPOSITIONS THEREOF</topic><topic>CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES</topic><topic>CULTURE MEDIA</topic><topic>ENZYMOLOGY</topic><topic>LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES</topic><topic>MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS</topic><topic>METALLURGY</topic><topic>MICROBIOLOGY</topic><topic>MICROORGANISMS OR ENZYMES</topic><topic>MUTATION OR GENETIC ENGINEERING</topic><topic>PROCESSES OF PREPARING SUCH COMPOSITIONS</topic><topic>PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS</topic><topic>SPIRITS</topic><topic>VINEGAR</topic><topic>WINE</topic><toplevel>online_resources</toplevel><creatorcontrib>YU KE</creatorcontrib><creatorcontrib>HE PENGHAI</creatorcontrib><creatorcontrib>LIN XIAOJIAN</creatorcontrib><creatorcontrib>MA YINI</creatorcontrib><creatorcontrib>HU YAOWEN</creatorcontrib><creatorcontrib>DING LINFENG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>YU KE</au><au>HE PENGHAI</au><au>LIN XIAOJIAN</au><au>MA YINI</au><au>HU YAOWEN</au><au>DING LINFENG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Probe combination, kit and method for detecting genetic susceptibility genes of ovarian cancer</title><date>2024-06-21</date><risdate>2024</risdate><abstract>The invention discloses a probe combination for detecting an ovarian cancer genetic susceptibility gene. The probe combination comprises at least one of sequences as shown in SEQ ID NO 1-641. The invention also discloses a kit comprising the probe combination and a method for detecting the genetic susceptibility gene of the ovarian cancer by using the kit. According to the present invention, the ovarian cancer genetic susceptibility related genes such as ATM, BRCA1, BRCA2, BRIP1, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, PTEN, RAD51C, RAD51D and STK11 can be detected at one time by using the hybrid capture method; the probe is wide in coverage, high in sequencing depth and capable of detecting embryonic line variation of all exon regions of a target gene. According to the invention, all related diseases of ovarian cancer genetic susceptibility related genes can be reported, and genetic modes corresponding to the diseases are provided.
本发明公开了一种检测卵巢癌遗传易感基因的探针组合，包括SEQ ID NO 1～641所示序列中的至少一种。并公开了包括所述探针组合的试剂盒以及利用所述试剂盒检</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | chi ; eng |
| recordid | cdi_epo_espacenet_CN118222705A |
| source | esp@cenet |
| subjects | BEER BIOCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE |
| title | Probe combination, kit and method for detecting genetic susceptibility genes of ovarian cancer |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-13T14%3A07%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=YU%20KE&rft.date=2024-06-21&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECN118222705A%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |