Probe combination, kit and method for detecting genetic susceptibility genes of ovarian cancer

The invention discloses a probe combination for detecting an ovarian cancer genetic susceptibility gene. The probe combination comprises at least one of sequences as shown in SEQ ID NO 1-641. The invention also discloses a kit comprising the probe combination and a method for detecting the genetic susceptibility gene of the ovarian cancer by using the kit. According to the present invention, the ovarian cancer genetic susceptibility related genes such as ATM, BRCA1, BRCA2, BRIP1, EPCAM, MLH1, MSH2, MSH6, PALB2, PMS2, PTEN, RAD51C, RAD51D and STK11 can be detected at one time by using the hybrid capture method; the probe is wide in coverage, high in sequencing depth and capable of detecting embryonic line variation of all exon regions of a target gene. According to the invention, all related diseases of ovarian cancer genetic susceptibility related genes can be reported, and genetic modes corresponding to the diseases are provided. 本发明公开了一种检测卵巢癌遗传易感基因的探针组合，包括SEQ ID NO 1～641所示序列中的至少一种。并公开了包括所述探针组合的试剂盒以及利用所述试剂盒检