Formaldehyde regeneration type near-infrared fluorescent probe as well as preparation method and application thereof

The invention provides a formaldehyde regeneration type near-infrared fluorescent probe and a preparation method and application thereof.The chemical structure of the near-infrared fluorescent probe is as shown in the structural formula I. The probe can interact with formaldehyde in a high-sensitivity and high-selectivity mode, a strong near-infrared fluorescent signal is generated for analysis and detection, meanwhile, the same amount of formaldehyde molecules are released, and the formaldehyde regeneration type near-infrared fluorescent probe is obtained. The change of the local concentration of formaldehyde is avoided. The formaldehyde regeneration type near-infrared fluorescent probe has the advantages of novel structure, high formaldehyde selectivity, good imaging performance and the like, and has good application value in the aspect of detecting formaldehyde in a biological sample; and # imgabs0 #. 本发明提供一种甲醛再生型近红外荧光探针及其制备方法和应用，所述近红外荧光探针的化学结构如结构式I所示，该探针可高灵敏、高选择性的与甲醛相互作用，产生较强近红外荧光信号用于分析检测，同时释放等量的甲醛分子，避免甲醛